RNA Details
Disease Name
skin fibrosis
Tissue
skin
RNA Symbol
mir-29b-1
RNA ID
RNA Type
miRNA
Alteration Pattern
dysregulation
Species
homo sapiens
Detection Methods
enzyme-linked immunosorbent assay; emsa etc.
Target
TRANSCRIPTION FACTOR SPECIFICITY PROTEIN 1 (SP1)
Pathway
NA
PubMed ID
Title
MicroRNA-29b mediates fibrotic induction of human xylosyltransferase-I in human dermal fibroblasts via the Sp1 pathway
Year
2018
Function
A hitherto unidentified pathway of xt-i regulation via microrna-29b;Sp1 was determined in this study. Our observations will facilitate the understanding of complex molecular fibrotic pathways and provide new opportunities to investigate microrna-based antifibrotic tools.